Calvin Stengs gave Feyenoord the lead in first-half stoppage-time when his 30-yard free-kick evaded a poor attempt at a defensive wall.
Joe Hart saved a penalty after Lagerbielke received a second yellow card and substitute Holm soon got a straight red card in the 68th minute. Alireza Jahanbakhsh got the home side’s second goal.
Centre-back Lagerbielke was one of two summer signings in the Celtic starting line-up with Nat Phillips ruled out by an ankle injury. The other, winger Luis Palma, made his first start for the club.
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